Blar i forfatter "McKay, James D."

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    • Association between anthropometry and lifestyle factors and risk of B-cell lymphoma: An exposome-wide analysis 

      Hosnijeh, Fatemeh Saberi; Casabonne, Delphine; Nieters, Alexandra; Solans, Marta; Naudin, Sabine; Ferrari, Pietro; McKay, James D.; Benavente, Yolanda; Weiderpass, Elisabete; Freisling, Heinz; Severi, Gianluca; Ruault, Marie-Christine Boutron; Bonet, Catalina; Besson, Caroline; Agnoli, Claudia; Barricarte, Aurelio; Christakoudi, Sofia; Masala, Giovanna; Knuppel, Anika; Sacerdote, Carlotta; Bueno-De-Mesquita, Bas; Tumino, Rosario; Huerta, José María; Schulze, Matthias B.; Kaaks, Rudolf; Amiano, Pilar; Barranco, Miguel Rodriguez; Canzian, Federico; Späth, Florentin; Jerkeman, Mats; Rylander, Charlotta; Tjønneland, Anne; Olsen, Anja; Borch, Kristin Benjaminsen; Vermeulen, Roel (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-31)
      To better understand the role of individual and lifestyle factors in human disease, an exposome‐wide association study was performed to investigate within a single‐study anthropometry measures and lifestyle factors previously associated with B‐cell lymphoma (BCL). Within the European Prospective Investigation into Cancer and nutrition study, 2402 incident BCL cases were diagnosed from 475 426 ...

    • Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements 

      Smith-Byrne, Karl; Cerani, Agustin; Guida, Florence; Zhou, Sirui; Agudo, Antonio; Aleksandrova, Krasimira; Barricarte, Aurelio; Barranco, Miguel Rodríguez; Bochers, Christoph H.; Gram, Inger Torhild; Han, Jun; Amos, Christopher I.; Hung, Rayjean J.; Grankvist, Kjell; Nøst, Therese Haugdahl; Imaz, Liher; Chirlaque-López, María Dolores; Johansson, Mikael; Kaaks, Rudolf; Kühn, Tilman; Martin, Richard M.; McKay, James D.; Pala, Valeria; Robbins, Hilary A.; Sandanger, Torkjel M; Schibli, David; Schulze, Matthias B.; Travis, Ruth C.; Vineis, Paolo; Weiderpass, Elisabete; Brennan, Paul; Johansson, Mattias; Richards, J Brent (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-04)
      Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ...

    • Genome-wide association study identifies multiple risk loci for renal cell carcinoma 

      Scelo, Ghislaine; Purdue, Mark P.; Brown, Kevin M.; Johansson, Mattias; Wang, Zhaoming; Eckel-Passow, Jeanette E.; Ye, Yuanqing; Hofmann, Jonathan N.; Choi, Jiyeon; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Sampson, Joshua N.; Abedi-Ardekani, Behnoush; Besse, Celine; Blanche, Helene; Boland, Anne; Burdette, Laurie; Chabrier, Amelie; Durand, Geoffroy; Le Calvez-Kelm, Florence; Prokhortchouk, Egor; Robinot, Nivonirina; Skryabin, Konstantin G.; Wozniak, Magdalena B.; Yeager, Meredith; Basta-Jovanovic, Gordana; Dzamic, Zoran; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Szeszenia-Dabrowska, Neonila; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Baglietto, Laura; Boeing, Heiner; Khaw, Kay-Tee; Weiderpass, Elisabete; Ljungberg, Börje; Sitaram, Raviprakash T.; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Koppova, Kvetoslava; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Pharoah, Paul; Andreotti, Gabriella; Freeman, Laura E Beane; Koutros, Stella; Albanes, Demetrius; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Kraft, Peter; Preston, Mark A.; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Black, Amanda; Freedman, Neal D.; Huang, Wen-Yi; Anema, John G.; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Wood, Christopher; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Rothman, Nathaniel; Deleuze, Jean-Francois; McKay, James D.; Parker, Alexander S.; Wu, Xifeng; Houlston, Richard S.; Brennan, Paul; Chanock, Stephen J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-09)
      Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk ...

    • A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium 

      McKay, James D.; Truong, Therese; Gaborieau, V; Chabrier, Amelie; Chuang, Shu-Chun; Byrnes, G; Zaridze, D; Shangina, O; Szeszenia-Dabrowska, N; Lissowska, Jolanta; Rudnai, P; Fabianova, E; Bucur, A; Bencko, V; Holcatova, I; Janout, V; Foretova, L; Lagiou, Pagona; Trichopoulos, Dimitrios; Benhamou, S; Ahrens, Wolfgang; Bouchardy, C; Merletti, F; Richiardi, L; Talamini, R; Simonato, L; Barzan, L; Kjærheim, Kristina; Macfarlane, G; Agudo, Antonio; Macfarlane, Tatiana V.; Canova, C; Castellsague, X; Conway, DI; Lowry, R; Healy, CM; McKinney, PA; Toner, ME; Znaor, A; Menezes, A; Curado, MP; Koifman, S; Neto, JE; Wünsch-Filho, V; Boccia, S; Arzani, D; Garrote, LF; Cadoni, G; Olshan, AF; Weissler, MC; Luo, JC; Funkhouser, WK; Lubinski, Jan; Lener, M; Trubicka, J; Schwartz, SM; Oszutowska, D; Doody, DR; Chen, C; Fish, S; Lazarus, P; Muscat, JE; Gallagher, CJ; Zhang, Zuo-Feng; Chang, SC; Wei, QY; Sturgis, EM; Franceschi, S; Kelsey, KT; Wang, LE; Herrero, R; Marsit, CJ; McClean, MD; Romkes, M; Nelson, HH; Buch, S; Nukui, T; Zhong, SL; Lacko, M; Manni, JJ; McLaughlin, J; Hung, RJ; Peters, WHM; Vatten, Lars Johan; Njølstad, Inger; Goodman, GE; Field, JK; Palli, D; Liloglou, T; Clavel-Chapelon, F; Vineis, P; Krogh, V; Tumino, R; Panico, S; Martinez, Carmen; Gonzalez, CA; Quiros, JR; Navarro, C; Larranaga, N; Khaw, KT; Ardanaz, E; Key, T; Peeters, PHM; Bueno-De-Mesquita, H. Bas; Boeing, H; Overvad, K; Trichopoulou, A; Linseisen, J; Hallmans, G; Tjønneland, Anne; Riboli, Elio; Kumle, Merethe; Valk, K; Voodern, Tonu; Metspalu, Andres; Boland, A; Zelenika, D; Delepine, M; Foglio, M; Lechner, D; Blanché, Hélène; Gut, Ivo G.; Galan, P; Hashibe, Mia; Heath, Simon; Hayes, Richard B.; Lathrop, Mark; Boffetta, Paolo; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved in susceptibility to upper aero-digestive tract (UADT) cancers. Genome-wide genotyping was carried out using the Illumina HumanHap300 beadchips in 2,091 UADT cancer cases and ...

    • The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study 

      Johansson, Mattias; Carreras-Torres, Robert; Scelo, Ghislaine; Purdue, Mark P.; Mariosa, Daniela; Muller, David C.; Timpson, Nicholas J.; Haycock, Philip C.; Brown, Kevin M.; Wang, Zhaoming; Ye, Yuanqing; Hofmann, Jonathan N.; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Garnier, Jean-Guillaume; Blanche, Helene; Boland, Anne; Burdette, Laurie; Prokhortchouk, Egor; Skryabin, Konstantin G.; Yeager, Meredith; Radojevic-Skodric, Sanja; Ognjanovic, Simona; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Weiderpass, Elisabete; Ljungberg, Börje; Tumkur Sitaram, Raviprakash; Häggström, Christel; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Andreotti, Gabriella; Beane Freeman, Laura E.; Koutros, Stella; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Freedman, Neal D.; Parker, Alexander S.; Eckel-Passow, Jeanette E.; Huang, Wen-Yi; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Deleuze, Jean-François; Gunter, Marc; McKay, James D.; Wu, Xifeng; Houlston, Richard S.; Chanock, Stephen J.; Relton, Caroline; Richards, J. Brent; Martin, Richard M.; Davey Smith, George; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-03)
      <i>Background</i> - Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as proxies for putative risk factors and evaluated their relation to RCC risk in a mendelian randomization (MR) framework. This methodology limits bias due to confounding and is ...